IBSSD 1511: Molecular, Cellular and Tissue Structure and Function

This course spans four modules that cover cell and tissue structure, cell signaling and metabolism, molecular biology and inheritance, and nutrition and cancer. Module 1: Cell and Tissue Structure. The disciplines of Biochemistry and Histology cover general cell structure and function. Topics include cell structure, muscle, epithelium and connective tissue, amino acid and protein structure, enzyme regulation and hemoglobin as well as a virtual histology laboratory. Module 2: Cell Signaling and Metabolism. Topics include second messenger, catalytic and steroid signaling, regulation of membrane transport, intermediary metabolism and bioenergetics, carbohydrate, protein and lipid metabolism and the biochemical foundations of diabetes mellitus. Module 3: Molecular Biology and Inheritance. Topics include the human genome, DNA replication, repair and mutations, transcription, translation and trafficking, genetic risk, autosomal dominant, recessive, sex-linked, mitochondrial and multifactorial inheritance as well as chromosomal abnormalities, genetic screening, diagnosis and gene therapy. Module 4: Nutrition and Cancer. Topics include macronutrients, vitamins, alcohol, iron and mineral metabolism, malnutrition and obesity as well as apoptosis, regulation of the cell cycle, histopathology of cancer, the molecular basis of cancer, tumor promotion and cancer metabolism.